Drugest Pharmaceuticals
Injectable solution, 100 ml
Large Animals

Nova 500

Dipyrone (Metamizole)

Nova 500

Composition

Each 1 ml contains:

Dipyrone 500 mg

Properties

Dipyrone is a pyrazolone derivative similar to aminopyrine, thought to act like other non-steroidal agents by inhibiting cyclo-oxygenase-mediated production of prostaglandins. It has marked analgesic and antipyretic activity with slight anti-inflammatory effect, and reportedly antispasmodic activity against bradykinin-induced spasm of the intestinal tract.

Indications

Pain relief (colic, neuritis, neuralgia, tendovaginitis, and to calm animals during examination and treatment); inflammatory conditions (acute and chronic arthritis, lumbago, rheumatic disorders of muscles and joints); spastic conditions (colic, intestinal spasm, and abdominal or smooth muscle spasm).

Dosage & Administration

By I/M or slow I/V injection.

Active ingredient — Cattle: 50 mg/kg body weight. Horse: 10–20 mg/kg. Pigs: 50 mg/kg. Dogs & cats: 28 mg/kg.

Whole product — Cattle: 5 ml / 50 kg body weight. Horse: 10–20 ml (5–10 g) per adult horse. Pigs: 1 ml / 10 kg. Dogs & cats: 0.6 ml / 10 kg.

Warnings & Precautions

In horses, do not administer within 5 days of racing. Check blood picture after prolonged use. Not for use in poultry. Total daily dose should not exceed 300 mg/animal/day for dogs and cats, to prevent convulsions. Administer by I/M or slow I/V injection only — do not give by S/C injection.

Contraindications

Not for cattle producing milk for human consumption. Do not administer with phenylbutazone or barbiturate agents. Concomitant administration with chlorpromazine may cause serious hypothermia.

Side Effects

Agranulocytosis and leucopenia may develop with high doses.

Withdrawal Time

Meat: 28 days

Storage

Store in a cool place, away from direct sunlight.

Package

Glass vials of 30, 50, 100, 200, 250 & 500 ml.

Manufactured by Arabcomed for Drugest Pharmaceuticals Company. For veterinary use only.